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1

ChemInform Abstract: 4-Heterocyclylpiperidines as Selective High-Affinity Ligands at the Human Dopamine D4 Receptor.

M. ROWLEY, I. COLLINS, H. B. BROUGHTON, W. B. DAVEY, R. BAKER, F. EMMS, R. MARWOOD, SHIL PATEL, SMITA PATEL, C. I. RAGAN, S. B. FREEDMAN, R. BALL, P. D. LEESON

Journal:

Année:

1997

Fichier:

PDF, 33 KB

1997

2

ChemInform Abstract: 2-Aryltryptamines: Selective High-Affinity Antagonists for the h5-HT2A Receptor.

Graeme I. Stevenson, Adrian L. Smith, Stephen Lewis, Stephen G. Michie, Joseph G. Neduvelil, Smita Patel, Rosemarie Marwood, Shil Patel, Jose L. Castro

Journal:

Année:

2001

Fichier:

PDF, 34 KB

2001

3

2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor

Graeme I Stevenson, Adrian L Smith, Stephen Lewis, Stephen G Michie, Joseph G Neduvelil, Smita Patel, Rosemarie Marwood, Shil Patel, José L Castro

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2000

Langue:

english

Fichier:

PDF, 162 KB

english, 2000

4

Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands

Neil R. Curtis, Janusz J. Kulagowski, Paul D. Leeson, Mark P. Ridgill, Frances Emms, Stephen B. Freedman, Shil Patel, Smita Patel

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 195 KB

english, 1999

5

4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors

Kevin W. Moore, Katrine Bonner, Elizabeth A. Jones, Frances Emms, Paul D. Leeson, Rosemary Marwood, Shil Patel, Smita Patel, Michael Rowley, Steven Thomas, Robert W Carling

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 255 KB

english, 1999

6

3-(1-Piperazinyl)-4,5-dihydro-1H-benzo[g]indazoles: high affinity ligands for the human dopamine D4 receptor with improved selectivity over ion channels

Ian Collins, Michael Rowley, William B Davey, Frances Emms, Rosemarie Marwood, Shil Patel, Smita Patel, Alan Fletcher, Ian C Ragan, Paul D Leeson, Ann L Scott, Theodore Broten

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 238 KB

english, 1998

7

Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers

Terence G. Hamill, Stephen Krause, Christine Ryan, Celine Bonnefous, Steve Govek, T. Jon Seiders, Nicholas D.P. Cosford, Jeffrey Roppe, Ted Kamenecka, Shil Patel, Raymond E. Gibson, Sandra Sanabria, K

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 439 KB

english, 2005

8

Inverse agonist histamine H3 receptor PET tracers labelled with carbon-11 or fluorine-18

Terence G. Hamill, Nagaaki Sato, Makoto Jitsuoka, Shigeru Tokita, Sandra Sanabria, Waisi Eng, Christine Ryan, Stephen Krause, Norihiro Takenaga, Shil Patel, Zhizhen Zeng, David Williams Jr., Cyrille S

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 377 KB

english, 2009

9

Synthesis, characterization, and monkey PET studies of [18F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435

Eric D. Hostetler, Waisi Eng, Aniket D. Joshi, Sandra Sanabria-Bohórquez, Hiroshi Kawamoto, Satoru Ito, Stacey O'Malley, Stephen Krause, Christine Ryan, Shil Patel, Mangay Williams, Kerry Riffel, Gent

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2011

10

The synthesis and preclinical evaluation in rhesus monkey of [18F]MK-6577 and [11C]CMPyPB glycine transporter 1 positron emission tomography radiotracers

Terence G. Hamill, Waisi Eng, Andrew Jennings, Richard Lewis, Steven Thomas, Suzanne Wood, Leslie Street, David Wisnoski, Scott Wolkenberg, Craig Lindsley, Sandra M. Sanabria-BohÓRquez, Shil Patel, Ke

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2011

11

Screening Cascade and Development of Potential Positron Emission Tomography Radiotracers for mGluR5:In vitroandIn vivoCharacterization

Shil Patel, Obinna Ndubizu, Terence Hamill, A. Chaudhary, H. Donald Burns, R. Hargreaves, Raymond E. Gibson

Journal:

Molecular Imaging and Biology

Année:

2005

Langue:

english

Fichier:

PDF, 442 KB

english, 2005

12

Substituted pyrazoles as novel selective ligands for the human dopamine D4 receptor

Sylvie Bourrain, Ian Collins, Joseph G. Neduvelil, Michael Rowley, Paul D. Leeson, Smita Patel, Shil Patel, Frances Emms, Rosemarie Marwood, Kerry L. Chapman, Alan E. Fletcher, Graham A. Showell

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 255 KB

english, 1998

13

In vitro characterization of a γ-secretase radiotracer in mammalian brain

Shil Patel, Stacey O'Malley, Brett Connolly, Wensheng Liu, Richard Hargreaves, Cyrille Sur, Raymond E. Gibson

Journal:

Journal of Neurochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 503 KB

english, 2006

14

1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: A Selective High-Affinity Antagonist for the Human Dopamine D4 Receptor with Excellent Selectivity over Ion Channels

Carling, Robert W., Moore, Kevin W., Moyes, Christopher R., Jones, Elizabeth A., Bonner, Katrine, Emms, Frances, Marwood, Rosemary, Patel, Shil, Patel, Smita, Fletcher, Alan E.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 132 KB

english, 1999

15

The muscarinic receptor agonist L-658,903 modulates the in vivo accumulation of inositol monophosphates in mouse brain

Shil Patel, Stephen B. Freedman

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 596 KB

english, 1994

16

Stress-induced increase of cortical dopamine metabolism: attenuation by a tachykinin NK1 receptor antagonist

Peter H. Hutson, Shil Patel, Mark T. Jay, Cheryl L. Barton

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 212 KB

english, 2004

17

3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as High Affinity, Selective, and Orally Bioavailable h5-HT2A Receptor Antagonists†

Rowley, Michael, Hallett, David J., Goodacre, Simon, Moyes, Christopher, Crawforth, James, Sparey, Timothy J., Patel, Smita, Marwood, Rose, Patel, Shil, Thomas, Steven

Journal:

Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 234 KB

english, 2001

18

In vivo characterisation of novel efficacious muscarinic receptor agonists

Stephen B. Freedman, Elizabeth A. Harley, Rosemarie S. Marwood, Shil Patel

Journal:

European Journal of Pharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 539 KB

english, 1990

19

L-687,306: a functionally selective and potent muscarinic M1 receptor agonist

Stephen B. Freedman, Shil Patel, Elizabeth A. Harley, Leslie L. Iversen, Raymond Baker, Graham A. Showell, John Saunders, Alexander McKnight, Nigel Newberry, Kate Scholey, Richard Hargreaves

Journal:

European Journal of Pharmacology

Année:

1992

Langue:

english

Fichier:

PDF, 161 KB

english, 1992

20

Hypothermia induced by cholinomimetic drugs is blocked by galanin: possible involvement of ATP-sensitive K+ channels

Shil Patel, Peter H. Hutson

Journal:

European Journal of Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 817 KB

english, 1994

21

Characterisation of a chimeric hD3/D2 dopamine receptor expressed in CHO cells

George McAllister, Michael R. Knowles, Shil Patel, Rosemarie Marwood, Frances Emms, Guy R. Seabrook, Michael Graziano, Doreen Borkowski, Patricia J. Hey, Stephen B. Freedman

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 713 KB

english, 1993

22

Species differences in mGluR5 binding sites in mammalian central nervous system determined using in vitro binding with [18F]F-PEB

Shil Patel, Terence G. Hamill, Brett Connolly, Elaine Jagoda, Wenping Li, Raymond E. Gibson

Journal:

Nuclear Medicine and Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

23

In vivo site-directed radiotracers: a mini-review

Shil Patel, Raymond Gibson

Journal:

Nuclear Medicine and Biology

Année:

2008

Langue:

english

Fichier:

PDF, 329 KB

english, 2008

24

Effects of galanin on 8-OH-DPAT induced decrease in body temperature and brain 5-hydroxytryptamine metabolism in the mouse

Shil Patel, Peter H Hutson

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 297 KB

english, 1996

25

In vitro characterization of [3H]MethoxyPyEP, an mGluR5 selective radioligand

Shil Patel, Stephen M. Krause, Terence Hamill, Ashok Chaudhary, Donald H. Burns, Raymond A. Gibson

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 306 KB

english, 2003

26

An in vivo binding assay to determine central α1-adrenoceptor occupancy using [3H]prazosin

Shil Patel, Eva Fernandez-Garcia, Peter H Hutson, Smita Patel

Journal:

Brain Research Protocols

Année:

2001

Langue:

english

Fichier:

PDF, 422 KB

english, 2001

27

An In Vitro Assay for Predicting Successful Imaging Radiotracers

Shil Patel, Terence Hamill, Eric Hostetler, H.Donald Burns, Raymond E Gibson

Journal:

Molecular Imaging and Biology

Année:

2003

Langue:

english

Fichier:

PDF, 285 KB

english, 2003

28

Functional expression of human D3 dopamine receptors in differentiated neuroblastoma × glioma NG108–15 cells

Guy R. Seabrook, John A. Kemp, Stephen B. Freedman, Shil Patel, Heather A. Sinclair, George McAllister

Journal:

British Journal of Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 465 KB

english, 1994

29

5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors

Rowley, Michael, Broughton, Howard B., Collins, Ian, Baker, Raymond, Emms, Frances, Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Freedman, Stephen B., Leeson, Paul D.

Journal:

Journal of Medicinal Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 117 KB

english, 1996

30

4-Heterocyclylpiperidines as Selective High-Affinity Ligands at the Human Dopamine D4 Receptor

Rowley, Michael, Collins, Ian, Broughton, Howard B., Davey, William B., Baker, Raymond, Emms, Frances, Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Freedman, Stephen B., Ball, Richard

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 558 KB

english, 1997

31

Improving Outcome of Aplastic Anaemia with HLA-Matched Sibling Donor Hematopoietic Stem Cell Transplantation: An Experience of Gujarat Cancer and Research Institute (GCRI)

Raut, Shreeniwas S., Shah, Sandip A., Patel, Kinnari A., Shah, Kamlesh M., Anand, Asha S., Talati, Shailesh S., Panchal, Harsha P., Patel, Apurva A., Parikh, Sonia K., Parekh, Bhavesh B., Shukla, Shil

Journal:

Indian Journal of Hematology and Blood Transfusion

Année:

2015

Langue:

english

Fichier:

PDF, 249 KB

english, 2015

32

3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1 H -pyrrolo[2,3- b ]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D 4 Receptor

Kulagowski, Janusz J., Broughton, Howard B., Curtis, Neil R., Mawer, Ian M., Ridgill, Mark P., Baker, Raymond, Emms, Frances, Freedman, Stephen B., Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan

Journal:

Journal of Medicinal Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 105 KB

english, 1996

33

An HIV Type 1 Subtype B Founder Effect in Korea: gp160 Signature Patterns Infer Circulation of CTL-Escape Strains at the Population Level

Daniels, Rod S., Kang, Chun, Patel, Dina, Xiang, Zheng, Douglas, Nigel W., Zheng, Natalie N., Cho, Hae-Wol, Lee, Joo-Shil

Journal:

AIDS Research and Human Retroviruses

Année:

2003

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2003

34

Evaluating Retinal Toxicity of Intravitreal Caspofungin in the Mouse Eye

Mojumder, Deb K., Concepcion, Francis A., Patel, Shil K., Barkmeier, Andrew J., Carvounis, Petros E., Wilson, John H., Holz, Eric R., Wensel, Theodore G.

Journal:

Investigative Ophthalmology & Visual Science

Année:

2010

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2010

35

Acute Renal Infarction Presenting with Acute Abdominal Pain Secondary to Newly Discovered Atrial Fibrillation: A Case Report and Literature Review

Eltawansy, Sherif Ali, Patel, Shil, Rao, Mana, Hassanien, Samaa, Maniar, Mihir

Journal:

Case Reports in Emergency Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2014

36

Diagnostic and Therapeutic Challenges

Turaka, Kiran, Gordon, Alan J., Patel, Shil, Bryan, J. Shepard, Kwong, Henry M., Dugel, Pravin U., Arogyasami, Roy M.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 204 KB

english, 2013

37

A case of fatal Guillain–Barre syndrome from anti-PD1 monoclonal antibody use

Jacob, Aasems, Unnikrishnan, Dileep C., Mathew, Aju, Thyagarajan, Braghadheeswar, Patel, Shil

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 365 KB

english, 2016

38

Preclinical pharmacology and pharmacokinetics of CERC-301, a GluN2B-selective N -methyl-D-aspartate receptor antagonist

Garner, Rachel, Gopalakrishnan, Shobha, McCauley, John A., Bednar, Rodney A., Gaul, Stanley L., Mosser, Scott D., Kiss, Laszlo, Lynch, Joseph J., Patel, Shil, Fandozzi, Christine, Lagrutta, Armando, B

Journal:

Pharmacology Research & Perspectives

Année:

2015

Langue:

english

Fichier:

PDF, 302 KB

english, 2015

39

Extracardiac manifestations of atrial myxomas

Thyagarajan, Braghadheeswar, Kumar, Monisha Priyadarshini, Patel, Shil, Agrawal, Abhinav

Journal:

Journal of the Saudi Heart Association (Elsevier)

Année:

2016

Langue:

english

Fichier:

PDF, 544 KB

english, 2016

40

Pneumopericardium Due to Delayed Esophageal Leak After Per Oral Endoscopic Myotomy (POEM)

Lourdusamy, Dennisdhilak, Patel, Shil, Thyagarajan, Braghadheeswar, Anthony J, Squillaro, Gorcey, Steven, Kramer, Violet

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 97 KB

english, 2016

41

Advancing Drug Discovery and Development Using Molecular Imaging (ADDMI): an Interest Group of the World Molecular Imaging Society and an Inaugural Session on Positron Emission Tomography (PET)

Patel, Shil, Schmidt, Karl, Hesterman, Jacob, Hoppin, Jack

Journal:

Molecular Imaging and Biology

Année:

2017

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2017

42

An Unusual Case of Esophageal Foreign Body Obstruction

Patel, Shil, Laufgraben, Marc, Terrany, Ben

Journal:

Gastroenterology

Année:

2017

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2017

43

The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils

Josephson, Lee, Stratman, Nancy, Liu, YuTing, Qian, Fang, Liang, Steven H., Vasdev, Neil, Patel, Shil

Journal:

Molecular Imaging

Année:

2018

Langue:

english

Fichier:

PDF, 322 KB

english, 2018

44

Extracellular matrix degradation products downregulate neoplastic esophageal cell phenotype

Saldin, Lindsey Tamiko, Patel, Shil, Zhang, Li, Huleihel, Luai, Hussey, George S., Nascari, David Gabriele, Quijano, Lina Maria, Li, Xue, Raghu, Divya, Bajwa, Anant Kaur, Smith, Nicholas G., Chung, Ch

Journal:

Tissue Engineering Part A

Année:

2018

Langue:

english

Fichier:

PDF, 6.42 MB

english, 2018

45

714 - Extracellular Matrix Hydrogel Downregulates Neoplastic Esophageal Cell Phenotype

Saldin, Lindsey T., Patel, Shil, Zhang, Li, Huleihel, Luai, Quijano, Lina M., Bajwa, Anant, Raghu, Divya, Nascari, David, Chung, Chris, Smith, Nicholas, Hussey, George, Omstead, Ashten N., Kosovec, Ju

Journal:

Gastroenterology

Année:

2018

Langue:

english

Fichier:

PDF, 809 KB

english, 2018

46

Preclinical In Vitro and In Vivo Characterization of Synaptic Vesicle 2A–Targeting Compounds Amenable to F-18 Labeling as Potential PET Radioligands for Imaging of Synapse Integrity

Patel, Shil, Knight, Ashley, Krause, Stephen, Teceno, Tyler, Tresse, Cedric, Li, Songye, Cai, Zhengxin, Gouasmat, Alexandra, Carroll, Vincent M., Barret, Olivier, Gottmukkala, Vijay, Zhang, Wenjie, Xi

Journal:

Molecular Imaging and Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2019

47

Socioeconomic Impact on Mortality and Outcomes in Patients With Acute Liver Failure

Golikov, Edwin, Patel, Shil, Salem, Suhail, Bhatia, Taruna, Vinod, Jeevan

Journal:

American Journal of Gastroenterology

Année:

2018

Fichier:

PDF, 1.27 MB

2018

48

Endoscopic Resection of a Gastric Metastasis From Renal Cell Carcinoma

Golikov, Edwin, Patel, Shil, Abadier, Michael, Iyengar, Devarajan, Ramasamy, Kovil, Dedousis, John

Journal:

American Journal of Gastroenterology

Année:

2018

Fichier:

PDF, 1.58 MB

2018

49

Intracardiac metastasis of high-grade sarcoma of the neck causing right ventricular outflow obstruction

Thyagarajan, Braghadheeswar, Unnikrishnan, Dileep, Patel, Shil, Alagusundaramoorthy, Sayee Sundar

Journal:

BMJ Case Reports

Année:

2016

Fichier:

PDF, 386 KB

2016

50

Spontaneous rectus sheath haematoma secondary to severe coughing in a patient with no other precipitating factors

Patel, Shil, Thyagarajan, Braghadheeswar, Lalani, Ishan

Journal:

BMJ Case Reports

Année:

2016

Fichier:

PDF, 679 KB

2016